SCHEMBL2912656

SCHEMBL2912656

Cc1ccc(Cn2nc(C(=O)O)c3c2-c2ccc(Cl)cc2CCC3)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.63
CNR1 P21554 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906710 0.92 CNR2 (0.63) CNR2CNR1
SCHEMBL2912693 0.88 CNR2 (0.60) CNR2CNR1
SCHEMBL2911590 0.81 CNR2 (0.60) CNR2
SCHEMBL13218690 0.79 CNR2 (1.00) CNR2CNR1
SCHEMBL2914169 0.78 CNR2 (0.45) CNR2CNR1
SCHEMBL2913905 0.78 CNR2 (0.45) CNR2CNR1
SCHEMBL2187287 0.78 CNR2 (0.74) CNR2CNR1
SCHEMBL13175934 0.76 CNR2 (0.62) CNR2CNR1
SCHEMBL5806383 0.75 FABP4 (0.49)
SCHEMBL13175889 0.74 CNR2 (0.54) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130017149-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2013-01-17 US disclosed
US-20130017149-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2013-01-17 US disclosed
US-20130017149-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2013-01-17 US disclosed
EP-2223914-A1 Tricyclic condensed pyrazole derivatives as CB1 inhibitors Neuroscienze Pharmaness S.C. A R.L. (IT) 2010-09-01 EP disclosed
EP-2223913-A1 Tricyclic pyrazole derivatives and microemulsions thereof as CB1- and/or CB2-inhibitors Neuroscienze Pharmaness S.C. A R.L. (IT) 2010-09-01 EP disclosed
US-20100215741-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2010-08-26 US disclosed
US-20100215741-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2010-08-26 US disclosed
US-20100215741-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2010-08-26 US disclosed
US-20100216785-A1 PHARMACEUTICAL COMPOSITIONS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2010-08-26 US disclosed
US-20100216785-A1 PHARMACEUTICAL COMPOSITIONS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2010-08-26 US disclosed
US-20100216785-A1 PHARMACEUTICAL COMPOSITIONS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100215741-A1 PHARMACEUTICAL COMPOUNDS CNR1, CNR2, TRPV1 CNR2 2/4885CNR1 1/4885
US-20130017149-A1 PHARMACEUTICAL COMPOUNDS CNR1, CNR2, TRPV1 CNR2 2/4885CNR1 1/4885
US-20100216785-A1 PHARMACEUTICAL COMPOSITIONS CNR2, CNR1, SGMS2 CNR2 1/4885CNR1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.