SCHEMBL29126958

SCHEMBL29126958

Cc1ccc2ncc3cccn3c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
KDM4E B2RXH2 7/20 0.62
HSD17B10 Q99714 3/20 0.62
GAA P10253 2/20 0.62
HPGD P15428 2/20 0.62
GLA P06280 1/20 0.62
PDE10A Q9Y233 1/20 0.44
ADORA3 P0DMS8 2/20 0.43
ADORA1 P30542 2/20 0.43
ADORA2A P29274 1/20 0.43
IKBKB O14920 1/20 0.41
MAPT P10636 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
CHEK1 O14757 1/20 0.41
LIMK1 P53667 1/20 0.41
MAPK14 Q16539 1/20 0.41
PTPN1 P18031 2/20 0.39
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
RAB9A P51151 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31612371 0.87 ALDH1A1 (0.62) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL30657608 0.81 ALDH1A1 (0.59) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29126962 0.81 ALDH1A1 (0.59) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29126959 0.80 ALDH1A1 (0.62) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29126973 0.80 KDM4E (0.62) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29126956 0.80 KDM4E (0.62) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29126964 0.80 ALDH1A1 (0.57) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29673192 0.77 KDM4E (1.00) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL1078583 0.77 KDM4E (1.00) ALDH1A1KDM4EHSD17B10GAAHPGD
SCHEMBL29229059 0.76 ALDH1A1 (0.53) ALDH1A1KDM4EHSD17B10GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118091-A Preparation method of 1-chloropyrrolo [1,2-a ] quinoxaline and derivatives thereof 石河子大学 2025-06-10 CN disclosed
CN-117143104-A Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof 陕西科技大学 2023-12-01 CN disclosed