Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676942 | 1.00 | NOS3 (0.33) | NOS3NOS1NOS2FEN1ALOX5AP | |
| SCHEMBL30676939 | 0.91 | NOS3 (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL29127755 | 0.91 | NOS3 (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL30676800 | 0.78 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL29127749 | 0.78 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL29127752 | 0.76 | FGFR4 (0.34) | NOS3NOS1NOS2FEN1ALOX5AP | |
| SCHEMBL30676957 | 0.76 | FGFR4 (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL30676959 | 0.76 | FGFR4 (0.34) | NOS3NOS1NOS2FEN1ALOX5AP | |
| SCHEMBL31010861 | 0.75 | NPC1 (0.49) | — | |
| SCHEMBL12136645 | 0.72 | CYP11B2 (0.35) | NOS3NOS1NOS2FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229208-B | Condensed ring compound, preparation method and medical application thereof | 上海泽德曼医药科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117229208-A | Condensed ring compound, preparation method and medical application thereof | 上海泽德曼医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |