⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878153 | 0.80 | — | — | |
| SCHEMBL31212984 | 0.80 | — | — | |
| SCHEMBL31205761 | 0.80 | — | — | |
| SCHEMBL7887292 | 0.80 | — | — | |
| SCHEMBL3659441 | 0.80 | — | — | |
| SCHEMBL15871027 | 0.78 | RAB9A (0.63) | — | |
| SCHEMBL16597642 | 0.78 | RAB9A (0.63) | — | |
| SCHEMBL17185663 | 0.76 | — | — | |
| SCHEMBL3715282 | 0.75 | — | — | |
| SCHEMBL445202 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894396-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | Ideaya Biosciences, Inc. (US) | 2021-10-20 | — | — | EP | claimed |
| CN-113166078-A | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-106749268-B | Heteroaromatic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-10-09 | — | — | CN | claimed |
| WO-2020123395-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-06-18 | — | — | WO | claimed |
| CN-110117239-A | Asymmetric trithio class compound and its synthetic method and application | 华东师范大学 | 2019-08-13 | — | — | CN | claimed |
| US-20170056398-A1 | SUBSTITUTED PYRIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | ROCHE PALO ALTO LLC (US) | 2017-03-02 | — | — | US | claimed |
| US-20160362395-A1 | INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS | ROCHE PALO ALTO LLC (US) | 2016-12-15 | — | — | US | claimed |
| US-9512112-B2 | Substituted pyridines as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2016-12-06 | — | — | US | claimed |
| US-9440956-B2 | Indole, indazole and benzimidazole arylamides as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2016-09-13 | — | — | US | claimed |
| EP-2445889-B1 | NOVEL BENZOXAZOLONE -SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-08-10 | — | — | EP | claimed |
| WO-2005123719-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-12-29 | — | — | WO | claimed |
| EP-1590358-A1 | 9-KETOSPINOSYN DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2005-11-02 | — | — | EP | claimed |
| EP-1347957-B1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-07 | — | — | EP | claimed |
| US-20050192339-A1 | Compounds | BIOVITRUM AB (SE) | 2005-09-01 | — | — | US | claimed |
| WO-2005051380-A1 | SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | claimed |
| WO-2005030757-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | claimed |
| WO-2004065402-A1 | 9-KETOSPINOSYN DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | claimed |
| US-20040082586-A1 | Delta 1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-29 | — | — | US | claimed |
| EP-1347957-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | Bayer CropScience AG (DE) | 2003-10-01 | — | — | EP | claimed |
| WO-2002046151-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-06-13 | — | — | WO | claimed |