⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499883 | 0.85 | RAB9A (0.38) | — | |
| SCHEMBL4446882 | 0.81 | CYP2D6 (0.40) | — | |
| SCHEMBL5305671 | 0.80 | RAB9A (0.46) | — | |
| SCHEMBL5305673 | 0.80 | RAB9A (0.46) | — | |
| SCHEMBL3938070 | 0.80 | KDM4E (0.40) | — | |
| SCHEMBL27817072 | 0.79 | — | — | |
| SCHEMBL291278 | 0.75 | — | — | |
| SCHEMBL15871027 | 0.74 | RAB9A (0.63) | — | |
| SCHEMBL16597642 | 0.74 | RAB9A (0.63) | — | |
| SCHEMBL17185663 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| CN-111511465-B | Method for producing organic silicon dioxide material and use thereof | 埃克森美孚科技工程公司 | 2023-06-06 | — | — | CN | disclosed |
| US-11325111-B2 | Catalysts and methods of making the same | EXXONMOBIL RESEARCH & ENGINEERING COMPANY (US) | 2022-05-10 | — | — | US | disclosed |
| CN-109311001-B | Organosilica polymer catalyst and method for producing same | 埃克森美孚研究工程公司 | 2022-04-08 | — | — | CN | disclosed |
| US-11111352-B2 | Methods of producing organosilica materials and uses thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2021-09-07 | — | — | US | disclosed |
| CN-107001945-B | Aromatic hydrogenation catalyst and use thereof | 埃克森美孚研究工程公司 | 2020-12-18 | — | — | CN | disclosed |
| EP-3727677-A1 | METHODS OF PRODUCING ORGANOSILICA MATERIALS AND USES THEREOF | ExxonMobil Research and Engineering Company (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-107207735-B | Organosilica material | 埃克森美孚研究工程公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111511465-A | Method for producing organosilica materials and uses thereof | 埃克森美孚研究工程公司 | 2020-08-07 | — | — | CN | disclosed |
| US-5973156-A | Piperidine and tetrahydropyridine derivatives | MERCK SHARP & DOME LTD. (GB) | 1999-10-26 | — | — | US | disclosed |
| EP-0882699-A1 | AMINO COMPOUNDS AND ANGIOTENSIN IV RECEPTOR AGONISTS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0861245-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1998-09-02 | — | — | EP | disclosed |
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997019073-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| US-5616586-A | Tricyclic quinoxalinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| WO-1996040141-A1 | 4,5-BRIDGED QUINOXALINEDIONES AND QUINOLONES AND THE USE THEREOF AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ACEA PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0642508-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |