Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 6/20 | 0.31 |
| ▸ | MMP3 | P08254 | 5/20 | 0.31 |
| ▸ | MMP1 | P03956 | 4/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726212 | 0.83 | GPR84 (0.32) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL24237659 | 0.78 | CA12 (0.33) | — | |
| SCHEMBL11545034 | 0.76 | HDAC1 (0.44) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL4726215 | 0.76 | GPR84 (0.32) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL5038575 | 0.73 | CHRM1 (0.41) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL5033928 | 0.73 | CHRM1 (0.41) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL4726218 | 0.70 | GPR84 (0.33) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL8330667 | 0.68 | TDP1 (0.37) | TDP1ALDH1A1 | |
| SCHEMBL499817 | 0.68 | GPR84 (0.39) | GPR84TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL12315571 | 0.68 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222630-A1 | PROCESSES TO PREGABALIN | Generics (UK) Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009081208-A1 | PROCESSES TO PREGABALIN | GENERICS [UK] LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |