Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128286 | 0.83 | KMT2A (0.39) | ALDH1A1POLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL29128479 | 0.83 | ALDH1A1 (0.38) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL29128414 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1POLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL29128271 | 0.76 | MRGPRX4 (0.40) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29128319 | 0.73 | HDAC3 (0.46) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL30800058 | 0.73 | HDAC3 (0.46) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL29125762 | 0.72 | ALDH1A1 (0.69) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29128523 | 0.72 | LTA4H (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30800063 | 0.72 | LTA4H (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29128411 | 0.70 | NPC1 (0.52) | ALDH1A1POLBLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |