Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397021 | 0.77 | LMNA (0.42) | APPALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18179820 | 0.75 | CYP2A6 (0.40) | ALDH1A1HPGDMEN1KMT2AALOX15 | |
| SCHEMBL27509682 | 0.75 | APP (0.45) | APPALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL15189824 | 0.74 | KMT2A (0.50) | ALDH1A1HPGDMEN1KMT2AALOX15 | |
| SCHEMBL28168179 | 0.73 | APP (0.39) | APPALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL926427 | 0.73 | APP (0.52) | APPALDH1A1HPGDMEN1KMT2A | |
| 4-Dimethylaminophenol SCHEMBL9792507 | 0.73 | APP (0.73) | APPALDH1A1HPGDMEN1KMT2A | |
| 4-Dimethylaminophenol SCHEMBL224308 | 0.73 | APP (0.73) | APPALDH1A1HPGDMEN1KMT2A | |
| Hydroquinone SCHEMBL9711166 | 0.71 | CYP3A4 (0.67) | APPALDH1A1HPGDMEN1KMT2A | |
| Hydroquinone SCHEMBL11759122 | 0.71 | CYP3A4 (0.67) | APPALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997546-A | APOL1 inhibitors and methods of use | 梅兹治疗公司 | 2023-11-03 | — | — | CN | disclosed |