Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168182 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL27700429 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL27450285 | 0.79 | TDP1 (0.48) | ALDH1A1MEN1KMT2AALOX15RECQL | |
| SCHEMBL27294646 | 0.78 | HTT (0.43) | ALDH1A1MEN1KMT2AALOX15NPC1 | |
| SCHEMBL27297501 | 0.76 | CYP2A6 (0.55) | ALDH1A1HPGDHSD17B10MAPTKDM4E | |
| SCHEMBL27350154 | 0.75 | — | — | |
| SCHEMBL27809709 | 0.75 | ALDH1A1 (0.41) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27787739 | 0.74 | MAPT (0.42) | ALDH1A1MEN1KMT2AHPGDRECQL | |
| SCHEMBL29128236 | 0.73 | APP (0.45) | APPESR1CRHBPCRHR2TLR9 | |
| SCHEMBL27397021 | 0.70 | LMNA (0.42) | APPESR1CRHBPCRHR2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816527-A | Nitrogen-containing heteroaryl compounds and their use in increasing endogenous erythropoietin | FIBROGEN INC (US) | 2006-08-09 | — | — | CN | claimed |
| CN-107056799-B | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, application and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-101420980-A | The Compounds and methods for of treatment apoplexy | FIBROGEN INC (US) | 2009-04-29 | — | — | CN | disclosed |