Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128498 | 0.83 | GAA (0.43) | APPKMT2ANPC1RAB9AGAA | |
| SCHEMBL29128292 | 0.80 | APP (0.41) | APPKMT2ANPC1RAB9ASIRT2 | |
| SCHEMBL29128201 | 0.80 | RXRA (0.41) | KMT2ANPC1RAB9AGAARXRA | |
| SCHEMBL30799938 | 0.76 | MAOB (0.39) | NPC1RAB9AMAOBFFAR1MAOA | |
| SCHEMBL29128567 | 0.76 | MAOB (0.39) | NPC1RAB9AMAOBFFAR1MAOA | |
| SCHEMBL30799958 | 0.76 | GAA (0.42) | KMT2ANPC1RAB9AGAATDP1 | |
| SCHEMBL29128249 | 0.76 | GAA (0.42) | KMT2ANPC1RAB9AGAATDP1 | |
| SCHEMBL29128486 | 0.74 | HTR1A (0.42) | KMT2ANPC1RAB9AGAALMNA | |
| SCHEMBL29128378 | 0.72 | KDM4C (0.44) | NPC1RAB9ARXRARXRBMAOB | |
| SCHEMBL30799885 | 0.72 | KDM4C (0.44) | NPC1RAB9ARXRARXRBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |