Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128478 | 1.00 | GPR119 (0.43) | GPR119NPY2ROPRK1PKMSMN1; SMN2 | |
| SCHEMBL4286463 | 0.88 | GPR119 (0.49) | GPR119NPY2ROPRK1PKMSMN1; SMN2 | |
| SCHEMBL26966991 | 0.88 | GPR119 (0.57) | GPR119 | |
| SCHEMBL26966994 | 0.80 | CHRNA7 (0.45) | — | |
| SCHEMBL26966988 | 0.80 | CHRNA7 (0.45) | — | |
| SCHEMBL29128127 | 0.79 | ALDH1A1 (0.48) | GPR119PKMLMNAALDH1A1 | |
| SCHEMBL26966811 | 0.79 | ALDH1A1 (0.48) | GPR119PKMLMNAALDH1A1 | |
| SCHEMBL26967018 | 0.78 | ALDH1A1 (0.47) | GPR119PKMLMNAALDH1A1 | |
| SCHEMBL26966997 | 0.77 | GPR119 (0.42) | GPR119NPY2RPKMLMNAALDH1A1 | |
| SCHEMBL20745908 | 0.76 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997546-A | APOL1 inhibitors and methods of use | 梅兹治疗公司 | 2023-11-03 | — | — | CN | disclosed |