Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836602 | 0.92 | SMN1; SMN2 (0.40) | POLBALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL7839976 | 0.85 | TSHR (0.44) | POLBALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL13664666 | 0.85 | POLB (0.34) | POLBALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL27800265 | 0.82 | ALDH1A1 (0.35) | POLBALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL13667807 | 0.78 | ALDH1A1 (0.37) | POLBALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL14629536 | 0.73 | POLB (0.34) | POLBALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL13328607 | 0.73 | POLB (0.34) | POLBALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL23509910 | 0.72 | SMN1; SMN2 (0.38) | POLBALDH1A1OPRM1SMN1; SMN2LMNA | |
| SCHEMBL7547696 | 0.72 | NPSR1 (0.47) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13913464 | 0.72 | POLB (0.33) | POLBALDH1A1OPRM1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263922-A | Heterocyclic compounds as AT2R agonists | 武汉人福创新药物研发中心有限公司 | 2023-12-22 | — | — | CN | disclosed |