Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243441 | 0.98 | NPSR1 (0.46) | NPSR1CYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL7836602 | 0.77 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1274802 | 0.77 | NPSR1 (0.52) | NPSR1CYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL1274800 | 0.77 | NPSR1 (0.52) | NPSR1CYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL4187606 | 0.72 | CYP2C19 (0.35) | — | |
| SCHEMBL29128570 | 0.72 | POLB (0.36) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4435261 | 0.71 | NPSR1 (0.46) | NPSR1CYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL14475938 | 0.71 | CHRM1 (0.33) | NPSR1LMNA | |
| SCHEMBL4099215 | 0.71 | NPSR1 (0.46) | NPSR1CYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL28107550 | 0.70 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210324-A1 | SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS | Chirotech Technology Limited (GB) | 2002-06-05 | — | — | EP | claimed |
| WO-2001017952-A1 | SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2001-03-15 | — | — | WO | claimed |