Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.39 |
| ▸ | GSR | P00390 | 3/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128708 | 0.84 | MAPT (0.56) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL5099519 | 0.80 | MAPT (0.61) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL31515714 | 0.78 | MAPT (0.59) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL29128699 | 0.76 | MEN1 (0.50) | MAPTHTTPOLBTDP1L3MBTL1 | |
| SCHEMBL3486254 | 0.76 | MAPT (0.57) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL11628945 | 0.76 | MAPT (0.57) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL27737344 | 0.73 | MAPT (0.56) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL29636874 | 0.72 | MAPT (0.59) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL1242494 | 0.72 | MAPT (0.59) | MAPTHTTFGFR4POLBTDP1 | |
| SCHEMBL9041742 | 0.72 | MAPT (0.55) | MAPTHTTL3MBTL1TXNRD1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263873-A | 1, 4-benzodiazepine compounds and application thereof in preparation of antitumor drugs | 复旦大学 | 2023-12-22 | — | — | CN | disclosed |