Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628945 | 0.86 | MAPT (0.57) | MAPTHTTFGFR4KMT2AMAPK1 | |
| SCHEMBL5099519 | 0.84 | MAPT (0.61) | MAPTHTTFGFR4MEN1KMT2A | |
| SCHEMBL31515714 | 0.82 | MAPT (0.59) | MAPTHTTFGFR4MEN1KMT2A | |
| SCHEMBL21522837 | 0.79 | MAPT (0.55) | MAPTHTTFGFR4MEN1KMT2A | |
| SCHEMBL1661669 | 0.79 | KMT2A (0.47) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL267725 | 0.77 | L3MBTL1 (0.44) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL9110385 | 0.77 | MAPT (0.53) | MAPTHTTFGFR4L3MBTL1POLB | |
| SCHEMBL1242494 | 0.77 | MAPT (0.59) | MAPTHTTFGFR4MAPK1SMN1; SMN2 | |
| SCHEMBL29636874 | 0.77 | MAPT (0.59) | MAPTHTTFGFR4MAPK1SMN1; SMN2 | |
| SCHEMBL29128704 | 0.76 | MAPT (0.56) | MAPTHTTFGFR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637650-B2 | Macromolecular nucleotide compounds and methods for using the same | GENOVOXX GMBH (DE) | 2014-01-28 | — | — | US | disclosed |
| US-20100029494-A1 | Macromolecular Nucleotide Compounds And Methods For Using The Same | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2010-02-04 | — | — | US | disclosed |
| US-20100029619-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2058309-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029619-A1 | FUSED HETEROCYCLIC COMPOUND | IRAK1, IL1R1, IRAK2 | MAPT 3292/4885HTT 3499/4885FGFR4 1407/4885 |
| US-20100029494-A1 | Macromolecular Nucleotide Compounds And Methods For Using The Same | DUT, SAMHD1, PNP | MAPT 2561/4885HTT 948/4885FGFR4 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.