SCHEMBL29128751

SCHEMBL29128751

COc1cc(OC)cc(-c2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.72
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
KDM4E B2RXH2 1/20 0.48
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
PKM P14618 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
STIM1 Q13586 1/20 0.47
ORAI1 Q96D31 1/20 0.47
CYP1A1 P04798 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572748 0.96 RXRA (0.67) RXRACA1CA2KDM4ECA12
SCHEMBL39734 0.87 CA1 (0.60) RXRACA1CA2KDM4ECA12
3,5-Dimethoxybenzoic Acid SCHEMBL503889 0.87 RXRA (0.64) RXRACA1CA2KDM4ECA12
SCHEMBL25508690 0.85 RXRA (0.58) RXRACA1CA2KDM4ECA12
SCHEMBL14150399 0.85 RXRA (0.69) RXRACA1CA2STIM1ORAI1
SCHEMBL30420728 0.85 RXRA (0.69) RXRACA1CA2STIM1ORAI1
3,5-Dimethoxybenzoic Acid SCHEMBL20592058 0.85 RXRA (0.62) RXRACA1CA2KDM4ECA12
Hydrochloric Acid SCHEMBL3361588 0.85 CA1 (0.58) RXRACA1CA2KDM4ECA12
3,5-Dimethoxybenzoic Acid SCHEMBL5668197 0.85 RXRA (0.62) RXRACA1CA2KDM4ECA12
Hydrochloric Acid SCHEMBL19118500 0.85 CA1 (0.58) RXRACA1CA2KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117049961-A Yeast dehydrogenase inhibitor derivative and synthesis method thereof 苏州君叶生物医药科技有限公司 2023-11-14 CN disclosed