Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.69 |
| ▸ | FABP1 | P07148 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 4/20 | 0.53 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.52 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14150399 | 1.00 | RXRA (0.69) | RXRAFABP1DHODHBRD4STIM1 | |
| SCHEMBL14878383 | 0.88 | RXRA (0.57) | RXRABRD4HSD17B1HSD17B2CYP1A1 | |
| SCHEMBL14150405 | 0.86 | RXRA (0.56) | RXRABRD4HSD17B1HSD17B2CA1 | |
| SCHEMBL2556922 | 0.85 | FABP1 (0.56) | RXRAFABP1STIM1ORAI1KMO | |
| SCHEMBL29572748 | 0.85 | RXRA (0.67) | RXRAFABP1DHODHHSD17B1HSD17B2 | |
| SCHEMBL29128751 | 0.85 | RXRA (0.72) | RXRASTIM1ORAI1CA1CA2 | |
| SCHEMBL2558136 | 0.85 | RXRA (0.73) | RXRASTIM1ORAI1HSD17B1HSD17B2 | |
| SCHEMBL2958179 | 0.85 | RXRA (0.68) | RXRAFABP1STIM1ORAI1HSD17B1 | |
| SCHEMBL2953758 | 0.85 | RXRA (0.63) | RXRABRD4STIM1ORAI1CA1 | |
| SCHEMBL14784048 | 0.84 | RXRA (0.54) | RXRAFABP1STIM1ORAI1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511731-B | Olefin compounds as modulators of the farnesol X receptor | 百时美施贵宝公司 | 2023-05-23 | — | — | CN | claimed |