Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.52 |
| ▸ | USP2 | O75604 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DDR2 | Q16832 | 7/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 3/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30934698 | 0.99 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL15846718 | 0.99 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| Lithium SCHEMBL30697091 | 0.97 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL23795672 | 0.88 | USP2 (0.50) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL30211921 | 0.87 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL4949624 | 0.86 | ALDH1A1 (0.55) | DDR1DDR2TSHRCYP2D6ABL1 | |
| Lithium Ion SCHEMBL29968172 | 0.86 | DDR1 (0.51) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| Lithium Ion SCHEMBL25341441 | 0.86 | DDR1 (0.51) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL30339886 | 0.85 | NOTUM (0.58) | DDR1USP2DDR2NTRK1NTRK3 | |
| SCHEMBL24071005 | 0.85 | CYP2D6 (0.53) | DDR1USP2CYP1A2CYP2C19DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062812-A | Indoline derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-11-14 | — | — | CN | disclosed |