Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.52 |
| ▸ | USP2 | O75604 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DDR2 | Q16832 | 7/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15846718 | 1.00 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL29129019 | 0.99 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| Lithium SCHEMBL30697091 | 0.99 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL23795672 | 0.89 | USP2 (0.50) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL30211921 | 0.88 | DDR1 (0.52) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL4949624 | 0.88 | ALDH1A1 (0.55) | DDR1DDR2TSHRCYP2D6ALDH1A1 | |
| Lithium Ion SCHEMBL29968172 | 0.87 | DDR1 (0.51) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| Lithium Ion SCHEMBL25341441 | 0.87 | DDR1 (0.51) | DDR1USP2CYP1A2CYP2C19DDR2 | |
| SCHEMBL30339886 | 0.86 | NOTUM (0.58) | DDR1USP2DDR2NTRK1NTRK3 | |
| SCHEMBL24071005 | 0.86 | CYP2D6 (0.53) | DDR1USP2CYP1A2CYP2C19DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190847-A1 | INDOLINE DERIVATIVES AS DDR1 AND DDR2 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190847-A1 | INDOLINE DERIVATIVES AS DDR1 AND DDR2 INHIBITORS | DDR1, DDR2, DDRGK1 | DDR1 1/4885USP2 2486/4885CYP1A2 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.