Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 19/20 | 0.66 |
| ▸ | CCNH | P51946 | 19/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.56 |
| ▸ | CDK1 | P06493 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | CDK9 | P50750 | 2/20 | 0.56 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.56 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.56 |
| ▸ | CCNK | O75909 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.56 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613431 | 1.00 | CDK7 (0.66) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL24510839 | 0.93 | CDK7 (0.67) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL24510838 | 0.91 | CDK7 (0.65) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL15649053 | 0.86 | CDK7 (0.55) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL29613463 | 0.86 | CDK7 (0.55) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL17150571 | 0.85 | CDK7 (0.70) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL19024448 | 0.85 | CDK7 (0.70) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL29129122 | 0.84 | CDK7 (0.57) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL29613456 | 0.84 | CDK7 (0.57) | CDK7CCNHCDK5CDK1CDK2 | |
| SCHEMBL17141301 | 0.83 | CDK7 (0.52) | CDK7CCNHCDK5CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279636-A | Methods and compounds for modulating myotonic muscular dystrophy type 1 | 设计治疗公司 | 2023-12-22 | — | — | CN | disclosed |