Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613561 | 1.00 | GAA (0.55) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2616222 | 0.88 | FKBP1A (0.65) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3216431 | 0.88 | GAA (0.53) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30257328 | 0.88 | GAA (0.53) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL931999 | 0.87 | MEN1 (0.72) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29613475 | 0.86 | GAA (0.54) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15156208 | 0.86 | GAA (0.51) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29129121 | 0.86 | GAA (0.54) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29129076 | 0.85 | GPR119 (0.55) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29613462 | 0.85 | GPR119 (0.55) | GAAMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279636-A | Methods and compounds for modulating myotonic muscular dystrophy type 1 | 设计治疗公司 | 2023-12-22 | — | — | CN | disclosed |