Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 10/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129362 | 0.94 | LCK (0.40) | LCKPIK3CGCA1CA2GAA | |
| SCHEMBL29129364 | 0.78 | PIK3CG (0.37) | PIK3CG | |
| SCHEMBL25147024 | 0.78 | CNR2 (0.40) | LCKPIK3CGGAA | |
| SCHEMBL25434541 | 0.77 | RAF1 (0.35) | LCKPIK3CGCA1CA2GAA | |
| SCHEMBL29129368 | 0.77 | ALDH1A1 (0.43) | PIK3CGGAA | |
| SCHEMBL15348877 | 0.75 | NPC1 (0.47) | LCKCA1CA2GAAPI4KB | |
| SCHEMBL31452252 | 0.75 | BRAF (0.48) | LCKPIK3CGBRAF | |
| SCHEMBL25309580 | 0.74 | MAPKAPK2 (0.38) | LCKPIK3CGCA1CA2BRAF | |
| SCHEMBL23214462 | 0.74 | LCK (0.46) | LCKCA1CA2PI4KB | |
| SCHEMBL1742407 | 0.74 | LCK (0.46) | LCKCA1CA2PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279896-A | Amino substituted pyrido ring compounds, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022214044-A1 | AMINE-SUBSTITUTED PYRIDINE FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-10-13 | — | — | WO | disclosed |