Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | MTOR | P42345 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129315 | 0.76 | PRKDC (0.40) | PDCD1CD274PDE3BPDE3APIK3CA | |
| SCHEMBL29987836 | 0.72 | TAAR1 (0.34) | PDCD1CD274PDE3BPDE3APIK3CA | |
| SCHEMBL31550288 | 0.65 | DYRK1A (0.43) | PIK3CAMTORPIK3CDPRKDC | |
| SCHEMBL7143060 | 0.64 | MAPK14 (0.52) | PDE3BPDE3APIK3CAMAPK14PIK3CD | |
| SCHEMBL4764267 | 0.64 | MAPK14 (0.48) | PDCD1CD274PDE3BPDE3APIK3CA | |
| SCHEMBL8786339 | 0.64 | ALDH1A1 (0.43) | PDCD1CD274PDE3BPDE3APIK3CA | |
| SCHEMBL18857842 | 0.63 | MAPK14 (0.47) | PIK3CAMTORMAPK14PIK3CD | |
| SCHEMBL20242282 | 0.63 | PDE3B (0.39) | PDE3BPDE3APIK3CAMTORPIK3CD | |
| SCHEMBL1565529 | 0.61 | — | — | |
| SCHEMBL30900883 | 0.61 | ALDH1A1 (0.43) | PDCD1CD274PIK3CAMAPK14PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279896-A | Amino substituted pyrido ring compounds, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-12-22 | — | — | CN | disclosed |