Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316450 | 0.85 | MAPT (0.74) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29171535 | 0.85 | MAPT (0.74) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6244040 | 0.84 | MAPT (0.72) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29129599 | 0.82 | ADORA3 (0.74) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29129516 | 0.82 | TNKS (0.55) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30876960 | 0.82 | MAPT (0.70) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4650064 | 0.82 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29129514 | 0.82 | TP53 (0.68) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29129596 | 0.82 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29129547 | 0.81 | KMT2A (0.65) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247370-A | Method for synthesizing thioflavonoids based on alkyne thiocarboxyl | 四川大学 | 2023-12-19 | — | — | CN | disclosed |