SCHEMBL29129697

SCHEMBL29129697

CCCCCCCCCCCCc1ccccc1S(=O)(=O)Nc1nccs1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.48
ALDH1A1 P00352 2/20 0.48
SCN1A P35498 9/20 0.47
SCN5A Q14524 9/20 0.47
SCN8A Q9UQD0 9/20 0.47
SCN1B Q07699 1/20 0.47
SCN9A Q15858 1/20 0.46
USP2 O75604 1/20 0.46
MAPT P10636 1/20 0.46
ESR2 Q92731 1/20 0.46
HSD17B10 Q99714 1/20 0.46
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2C9 P11712 1/20 0.44
EDNRA P25101 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25431214 0.83 ALDH1A1 (0.48) PKMALDH1A1SCN1ASCN5ASCN8A
SCHEMBL11364996 0.82 EDNRA (0.49) ALDH1A1LMNAEDNRA
SCHEMBL11358383 0.82 EDNRA (0.49) ALDH1A1LMNAEDNRA
SCHEMBL11891686 0.81 AKT1 (0.65)
SCHEMBL11355966 0.79 KDM4E (0.52) ALDH1A1HSD17B10LMNAKDM4ESMN1; SMN2
SCHEMBL11398588 0.77 AKT1 (0.49)
SCHEMBL11390455 0.76 AKT1 (0.51) LMNA
SCHEMBL11354551 0.76 MEN1 (0.56) ALDH1A1LMNASMN1; SMN2
SCHEMBL11458437 0.76 SMN1; SMN2 (0.54) PKMALDH1A1LMNAKDM4EEDNRA
SCHEMBL226295 0.74 RECQL (0.52) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947712-A Synthesis method of sulfonamide organic compound 苏州华道生物药业股份有限公司 2023-10-27 CN disclosed