Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 13/20 | 0.49 |
| ▸ | GAB1 | Q13480 | 5/20 | 0.47 |
| ▸ | IRS1 | P35568 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390455 | 0.85 | AKT1 (0.51) | AKT1GAB1IRS1ATM | |
| SCHEMBL11891686 | 0.80 | AKT1 (0.65) | AKT1GAB1PDPK1ABCB11AKT2 | |
| SCHEMBL11354551 | 0.78 | MEN1 (0.56) | — | |
| SCHEMBL29129697 | 0.77 | PKM (0.48) | — | |
| SCHEMBL11358383 | 0.76 | EDNRA (0.49) | — | |
| SCHEMBL11364996 | 0.76 | EDNRA (0.49) | — | |
| SCHEMBL226295 | 0.74 | RECQL (0.52) | — | |
| SCHEMBL11406272 | 0.74 | LIPG (0.46) | — | |
| SCHEMBL11355966 | 0.73 | KDM4E (0.52) | ATM | |
| SCHEMBL31367739 | 0.72 | CA12 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251664-A | IN A WATER IMMISCIBLE, LIQUID HYDROCARBON SOLVENT | HENKEL CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |