SCHEMBL29130076

SCHEMBL29130076

[CH2]CCCOCCOc1nc2cc(C(N)=O)ccc2c2cnccc12

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 19/20 0.51
CSNK2B P67870 19/20 0.51
CSNK2A1 P68400 9/20 0.44
PIM1 P11309 1/20 0.44
PIM2 Q9P1W9 1/20 0.44
PARP1 P09874 1/20 0.43
CSNK2A3 Q8NEV1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30694765 0.90 CSNK2A2 (0.51) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL25371037 0.90 CSNK2A2 (0.51) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL26048832 0.89 CSNK2A2 (0.53) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL25370631 0.89 CSNK2A2 (0.50) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL30694781 0.83 PARP1 (0.54) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL25370051 0.83 PARP1 (0.54) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL26049067 0.81 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL26049275 0.81 STING1 (0.48) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL26048829 0.81 CSNK2A2 (0.56) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL26048836 0.80 CSNK2A2 (0.53) CSNK2A2CSNK2BCSNK2A1PARP1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117295736-A Benzo [ C ] [2,6] naphthyridine derivatives, compositions thereof and therapeutic uses thereof 剑桥实业有限公司 2023-12-26 CN disclosed