Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL28401062 | 0.97 | DGKA (0.47) | DGKACES2CES1LMNACA1 | |
| SCHEMBL4626066 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL1238304 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL4002549 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL3290348 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL531198 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL6660916 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL496790 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL1156770 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL1930819 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295810-A | Hydratable concentrated surfactant compositions substantially free of isethionate | 联合利华知识产权控股有限公司 | 2023-12-26 | — | — | CN | disclosed |