Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL29130105 | 0.97 | DGKA (0.47) | DGKACES2CES1LMNACA1 | |
| SCHEMBL4626066 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL6660916 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL4002549 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL1930819 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL531198 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL1156770 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL496790 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL1238304 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM | |
| SCHEMBL3290348 | 0.91 | DGKA (0.55) | DGKACES2CES1LMNAPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115737514-A | Anti-dandruff shampoo and preparation method thereof | 莫少连 | 2023-03-07 | — | — | CN | claimed |
| CN-115463046-A | Bacteriostatic hand sanitizer easy to wash and preparation method thereof | 广州卓锐生物医药科技有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-115737514-A | Anti-dandruff shampoo and preparation method thereof | 莫少连 | 2023-03-07 | — | — | CN | disclosed |
| CN-115551828-A | Perfume composition | 西姆莱斯股份公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115463046-A | Bacteriostatic hand sanitizer easy to wash and preparation method thereof | 广州卓锐生物医药科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-115463046-A | Bacteriostatic hand sanitizer easy to wash and preparation method thereof | 广州卓锐生物医药科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-114727914-A | Product for the indirect transfer of a cosmetic active to the skin | 西姆莱斯股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-111110577-A | Mild mite-removing itching-relieving shower gel and preparation method thereof | 陈洁兴 | 2020-05-08 | — | — | CN | disclosed |