Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304803 | 0.81 | TSHR (0.42) | CYP1A2TP53ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11286333 | 0.80 | TSHR (0.45) | CYP1A2TP53ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7940300 | 0.77 | TSHR (0.42) | CYP1A2TP53ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL458041 | 0.77 | POLB (0.43) | CYP1A2TP53ALDH1A1MAPTTDP1 | |
| SCHEMBL6377117 | 0.77 | TSHR (0.49) | CYP1A2ALDH1A1MAPTTDP1ALOX15 | |
| SCHEMBL5585098 | 0.77 | LOXL2 (0.46) | ALDH1A1MAPTTDP1ALOX15CYP3A4 | |
| SCHEMBL3722491 | 0.75 | RIPK1 (0.45) | CYP1A2ALDH1A1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL231178 | 0.75 | KDM4E (0.42) | CYP1A2ALDH1A1MAPTTDP1CYP3A4 | |
| SCHEMBL27773763 | 0.75 | TSHR (0.39) | CYP1A2TP53ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6507123 | 0.75 | MAPT (0.40) | CYP1A2ALDH1A1MAPTTDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069679-A | N- (substituted phenyl) thiazole phenoxyacetamide compound and preparation method and application thereof | 湖南省农业生物技术研究所 | 2023-11-17 | — | — | CN | claimed |
| CN-117069679-A | N- (substituted phenyl) thiazole phenoxyacetamide compound and preparation method and application thereof | 湖南省农业生物技术研究所 | 2023-11-17 | — | — | CN | disclosed |