Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602452 | 1.00 | LRRK2 (0.37) | LRRK2PIK3CAPIK3R1CACNB4CACNA1A | |
| SCHEMBL29130963 | 0.92 | ERBB2 (0.39) | LRRK2PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30602477 | 0.92 | ERBB2 (0.39) | LRRK2PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29131007 | 0.85 | MBOAT4 (0.38) | LRRK2 | |
| SCHEMBL30602397 | 0.85 | MBOAT4 (0.38) | LRRK2 | |
| SCHEMBL2833261 | 0.82 | PIK3CA (0.38) | LRRK2PIK3CAPIK3R1CACNB4CACNA1A | |
| SCHEMBL3597491 | 0.74 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL2835065 | 0.73 | LRRK2 (0.40) | LRRK2PIK3CAPDE10A | |
| Hydrochloric Acid SCHEMBL3601390 | 0.73 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL1460108 | 0.73 | POLB (0.50) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |