Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.44 |
| ▸ | HTR2B | P41595 | 10/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29130939 | 0.79 | DRD2 (0.35) | HTR2CHTR2BHTR2ADRD2DRD3 | |
| SCHEMBL25272183 | 0.79 | SLC6A2 (0.44) | HTR2CHTR2BHTR2ADRD2DRD3 | |
| SCHEMBL16915136 | 0.77 | MAPT (0.52) | MEN1KMT2AMAPTTSHR | |
| SCHEMBL30602445 | 0.77 | MAPT (0.52) | MEN1KMT2AMAPTTSHR | |
| SCHEMBL16914916 | 0.76 | HDAC1 (0.47) | HTR2CHTR2BHTR2ADRD2DRD3 | |
| SCHEMBL9997046 | 0.75 | PIK3CA (0.46) | MEN1KMT2AMAPTMCHR1TSHR | |
| SCHEMBL30602385 | 0.75 | PIK3CA (0.46) | MEN1KMT2AMAPTMCHR1TSHR | |
| SCHEMBL18048553 | 0.75 | MCHR1 (0.45) | MCHR1 | |
| SCHEMBL29130908 | 0.75 | MAPT (0.48) | MAPTTSHR | |
| SCHEMBL12427204 | 0.74 | NOX4 (0.49) | DRD2DRD3MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |