Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850377 | 0.84 | ALDH1A1 (0.69) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL28850379 | 0.84 | ALDH1A1 (0.69) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL3147117 | 0.83 | ELANE (0.69) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL30881990 | 0.83 | ELANE (0.69) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL28746561 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL29565586 | 0.80 | ALDH1A1 (0.49) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL31186370 | 0.80 | ALDH1A1 (0.60) | ALDH1A1NPSR1SCN9AHSD17B10SMN1; SMN2 | |
| SCHEMBL28861277 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL7611042 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ELANENPSR1SCN9AHSD17B10 | |
| SCHEMBL16505715 | 0.74 | ALDH1A1 (0.81) | ALDH1A1NPSR1SCN9AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | disclosed |