Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147117 | 1.00 | ELANE (0.69) | ELANEALDH1A1NPSR1SCN9ATDP1 | |
| SCHEMBL16315749 | 0.86 | ELANE (0.59) | ELANEALDH1A1NPSR1TDP1CTSG | |
| SCHEMBL17377477 | 0.85 | SCN9A (0.63) | ELANESCN9ATDP1MAPTLMNA | |
| SCHEMBL7376832 | 0.84 | PARK7 (0.52) | ELANEALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL29131832 | 0.83 | ALDH1A1 (0.56) | ELANEALDH1A1NPSR1SCN9AP2RX1 | |
| SCHEMBL13233765 | 0.82 | ELANE (0.58) | ELANEALDH1A1NPSR1TDP1CTSG | |
| SCHEMBL31411532 | 0.82 | ELANE (0.58) | ELANEALDH1A1TDP1CTSGPRTN3 | |
| SCHEMBL31411584 | 0.82 | ELANE (0.47) | ELANEALDH1A1NPSR1SCN9ATDP1 | |
| SCHEMBL9387447 | 0.82 | CYP3A4 (0.54) | ELANEALDH1A1LMNA | |
| SCHEMBL21643744 | 0.81 | HDAC6 (0.58) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567350-A | Preparation method of indolone compound | 暨南大学 | 2024-02-20 | — | — | CN | disclosed |