Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131921 | 1.00 | PIK3CD (0.42) | PIK3CDCHEK2ANO1PIK3CAPIK3CB | |
| SCHEMBL28934423 | 0.90 | PIK3CD (0.46) | PIK3CDCHEK2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL28934426 | 0.90 | PIK3CD (0.46) | PIK3CDCHEK2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29276175 | 0.84 | PIK3CD (0.46) | PIK3CDCHEK2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29276170 | 0.84 | PIK3CD (0.46) | PIK3CDCHEK2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30624669 | 0.84 | IL1B (0.51) | — | |
| SCHEMBL29131879 | 0.84 | IL1B (0.51) | — | |
| SCHEMBL29131884 | 0.84 | IL1B (0.51) | — | |
| SCHEMBL21221766 | 0.79 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGUSP30 | |
| SCHEMBL28963149 | 0.78 | HCRTR1 (0.43) | PIK3CDPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969920-A | Fused pyridazine derivative, preparation method and medical application thereof | 上海辉启生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |