Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276170 | 1.00 | PIK3CD (0.46) | PIK3CDCHEK2PRMT5WDR77HPGDS | |
| SCHEMBL21221766 | 0.94 | PIK3CD (0.51) | PIK3CDUSP30PIK3CAPIK3CBPIK3CG | |
| SCHEMBL27224460 | 0.86 | BTK (0.45) | PIK3CDCHEK2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29131913 | 0.85 | BTK (0.40) | PIK3CDJAK2JAK1 | |
| SCHEMBL29131909 | 0.85 | BTK (0.40) | PIK3CDJAK2JAK1 | |
| SCHEMBL29131921 | 0.84 | PIK3CD (0.42) | PIK3CDCHEK2PRMT5WDR77USP30 | |
| SCHEMBL29131923 | 0.84 | PIK3CD (0.42) | PIK3CDCHEK2PRMT5WDR77USP30 | |
| SCHEMBL28934426 | 0.81 | PIK3CD (0.46) | PIK3CDCHEK2PRMT5WDR77USP30 | |
| SCHEMBL28934423 | 0.81 | PIK3CD (0.46) | PIK3CDCHEK2PRMT5WDR77USP30 | |
| SCHEMBL24840030 | 0.80 | PRMT5 (0.46) | PRMT5HPGDSUSP30ACKR3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |