Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908364 | 0.92 | CA2 (0.41) | KDM4EMEN1KMT2AHTTRXFP1 | |
| SCHEMBL2910291 | 0.89 | CNR2 (0.38) | KDM4EMEN1KMT2AHTTCNR2 | |
| SCHEMBL2915398 | 0.87 | MEN1 (0.41) | KDM4EMEN1KMT2AHTTRXFP1 | |
| SCHEMBL2907824 | 0.85 | MAPT (0.39) | KDM4EHTTRXFP1TSHRALDH1A1 | |
| SCHEMBL2915057 | 0.83 | CRBN (0.39) | KDM4EMEN1KMT2AHTTTSHR | |
| SCHEMBL2907766 | 0.83 | KMT2A (0.41) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2907218 | 0.82 | NR1H4 (0.38) | KDM4EMEN1KMT2ACFTRTSHR | |
| SCHEMBL2910755 | 0.82 | MAPT (0.38) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2913384 | 0.81 | NR1H4 (0.40) | KDM4EMEN1KMT2ACFTRTSHR | |
| SCHEMBL2915054 | 0.81 | NR1H4 (0.40) | KDM4EMEN1KMT2ACFTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |