Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 10/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913996 | 0.92 | CA1 (0.43) | CFTRADORA3ADRB3TBXA2RSLC6A2 | |
| SCHEMBL2913200 | 0.89 | KDM4E (0.40) | CNR2PABPC1EIF4HCFTRADORA3 | |
| SCHEMBL2912963 | 0.85 | ALDH1A1 (0.42) | CNR2CFTRMEN1KMT2AALDH1A1 | |
| SCHEMBL2913166 | 0.83 | XDH (0.38) | CFTRKDM4EMEN1KMT2AHTT | |
| SCHEMBL2913446 | 0.81 | ALDH1A1 (0.36) | CFTRMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2908364 | 0.81 | CA2 (0.41) | CFTRKDM4EMEN1KMT2AHTT | |
| SCHEMBL2910190 | 0.81 | GPR27 (0.42) | MEN1KMT2A | |
| SCHEMBL2910683 | 0.80 | ALDH1A1 (0.36) | CFTRALDH1A1LMNARAB9ABCL2L1 | |
| SCHEMBL1530928 | 0.80 | KDM4E (0.42) | CNR2CFTRADORA3ADRB3TBXA2R | |
| SCHEMBL2914837 | 0.80 | KMT2A (0.41) | KDM4EMEN1KMT2AHTTPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |