Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.85 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.85 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.85 |
| ▸ | MEN1 | O00255 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | THRB | P10828 | 7/20 | 0.78 |
| ▸ | BLM | P54132 | 7/20 | 0.78 |
| ▸ | RECQL | P46063 | 6/20 | 0.78 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.78 |
| ▸ | TOP2A | P11388 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514312 | 0.92 | S100A4 (0.90) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL1485948 | 0.92 | S100A4 (1.00) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL29648501 | 0.92 | S100A4 (1.00) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31238308 | 0.92 | S100A4 (0.86) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL28160200 | 0.91 | S100A4 (0.89) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31237243 | 0.91 | S100A4 (0.99) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL7805182 | 0.90 | S100A4 (0.86) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL7801104 | 0.90 | S100A4 (0.85) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL19732415 | 0.89 | MEN1 (0.87) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL10182791 | 0.89 | MEN1 (0.87) | S100A4PAX8HSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279952-A | Methods for treating cancer using subcutaneous administration of anti-PD 1 antibodies | 默沙东有限责任公司 | 2023-12-22 | — | — | CN | disclosed |