Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132190 | 0.80 | ITGB3 (0.40) | DRD3ITGB3ITGA2B | |
| SCHEMBL23860123 | 0.79 | DRD3 (0.34) | DRD3CHRM1SIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL28719987 | 0.78 | CHRM1 (0.42) | DRD3CHRM1MEN1KMT2AKDM4E | |
| SCHEMBL17467697 | 0.78 | DRD3 (0.40) | DRD3CHRM1SIGMAR1 | |
| SCHEMBL13451573 | 0.78 | DRD3 (0.40) | DRD3CHRM1SIGMAR1 | |
| SCHEMBL28719989 | 0.78 | CHRM1 (0.42) | DRD3CHRM1MEN1KMT2AKDM4E | |
| SCHEMBL23860101 | 0.77 | DRD3 (0.33) | DRD3CHRM1 | |
| SCHEMBL23860095 | 0.77 | USP2 (0.42) | CHRM1ALDH1A1CHRM3SMN1; SMN2 | |
| SCHEMBL26924284 | 0.77 | CACNA2D1 (0.40) | CHRM1ITGB3ITGA2B | |
| SCHEMBL26924970 | 0.77 | CACNA2D1 (0.40) | CHRM1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |