Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4158708 | 1.00 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| SCHEMBL21611 | 0.94 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| SCHEMBL27790589 | 0.94 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Acrylic Acid SCHEMBL16633112 | 0.93 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL131505 | 0.93 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Iodomethane SCHEMBL6686795 | 0.91 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29076630 | 0.91 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Chloromethane SCHEMBL1227510 | 0.91 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Methylamine SCHEMBL28734144 | 0.89 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| SCHEMBL112125 | 0.89 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | claimed |
| CN-115819684-A | Multifunctional ionic conductive high-toughness hydrogel and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-03-21 | — | — | CN | claimed |
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | disclosed |
| CN-115819684-A | Multifunctional ionic conductive high-toughness hydrogel and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-03-21 | — | — | CN | disclosed |