Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.55 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611 | 0.96 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| SCHEMBL27790589 | 0.96 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL131505 | 0.94 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29076630 | 0.93 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Chloromethane SCHEMBL1227510 | 0.93 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Acrylic Acid SCHEMBL16633112 | 0.91 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Acetic Acid SCHEMBL29132425 | 0.91 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Acetic Acid SCHEMBL4158708 | 0.91 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| Methylamine SCHEMBL28734144 | 0.91 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR | |
| SCHEMBL112125 | 0.91 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210186010-A1 | SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-06-24 | — | — | US | disclosed |
| US-20180346525-A1 | DIAGNOSTIC AND THERAPEUTIC QUORUM-SENSING-MANIPULATION MOLECULES THAT ARE TRACKABLE FOR HEALTH-CARE AND INDUSTRIAL SYSTEMS. | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-12-06 | — | — | US | disclosed |
| US-20180125066-A1 | SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-10 | — | — | US | disclosed |
| WO-2016176146-A1 | SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |
| JP-2004261260-A | ARTIFICIAL BLOOD VESSEL | NATIONAL CARDIOVASCULAR CENTER | 2004-09-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186010-A1 | SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS | ICAM1, QSOX1, CD47 | ZDHHC20 2749/4885ZDHHC2 4224/4885KDM4E 634/4885 |
| US-20180346525-A1 | DIAGNOSTIC AND THERAPEUTIC QUORUM-SENSING-MANIPULATION MOLECULES THAT ARE TRACKABLE FOR HEALTH-CARE AND INDUSTRIAL SYSTEMS. | Q6ZSR9, QARS1, QRFPR | ZDHHC20 2491/4885ZDHHC2 3177/4885KDM4E 2224/4885 |
| US-20180125066-A1 | SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS | ICAM1, QSOX1, CD47 | ZDHHC20 2682/4885ZDHHC2 4081/4885KDM4E 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.