Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | CA5A | P35218 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376961 | 1.00 | TDP1 (0.70) | TDP1LMNACA1CA2CA7 | |
| SCHEMBL30561865 | 0.83 | LMNA (0.79) | TDP1LMNACA1CA2CA7 | |
| Ethiazide SCHEMBL122238 | 0.83 | TDP1 (1.00) | TDP1LMNACA1CA2CA7 | |
| Ethiazide SCHEMBL30561875 | 0.83 | TDP1 (1.00) | TDP1LMNACA1CA2CA7 | |
| SCHEMBL29132639 | 0.83 | LMNA (0.79) | TDP1LMNACA1CA2CA7 | |
| SCHEMBL13685945 | 0.81 | TDP1 (0.79) | TDP1LMNACA1CA2CA7 | |
| Trichlormethiazide SCHEMBL25493 | 0.81 | LMNA (1.00) | TDP1LMNACA1CA2CA7 | |
| Trichlormethiazide SCHEMBL25492 | 0.81 | LMNA (1.00) | TDP1LMNACA1CA2CA7 | |
| Trichlormethiazide SCHEMBL29356280 | 0.81 | LMNA (1.00) | TDP1LMNACA1CA2CA7 | |
| Teclothiazide SCHEMBL309921 | 0.81 | LMNA (0.65) | TDP1LMNACA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836130-B | Synthesis method of 3, 4-dihydrobenzothiadiazine compound | 嘉实（湖南）医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116836130-A | Synthesis method of 3, 4-dihydrobenzothiadiazine compound | 嘉实（湖南）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |