Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL6103998 | 0.90 | MAPT (0.56) | MAPTALDH1A1TSHRTDP1CA12 | |
| Dimethylaminoethanol SCHEMBL20677258 | 0.90 | MAPT (0.75) | MAPTALDH1A1TSHRTDP1CA12 | |
| Monoethanolamine SCHEMBL3377894 | 0.85 | MAPT (0.50) | MAPTALDH1A1TSHRTDP1CA12 | |
| SCHEMBL29132828 | 0.85 | TDP1 (0.52) | MAPTALDH1A1TSHRTDP1CA12 | |
| Dimethylaminoethanol SCHEMBL28282228 | 0.84 | MAPT (0.75) | MAPTALDH1A1TSHRTDP1CA12 | |
| Dimethylaminoethanol SCHEMBL11289429 | 0.83 | MAPT (0.63) | MAPTALDH1A1TSHRTDP1CA12 | |
| SCHEMBL29132833 | 0.83 | TDP1 (0.50) | MAPTALDH1A1TSHRTDP1CA12 | |
| Ethylenediamine SCHEMBL6911410 | 0.82 | CA12 (0.53) | MAPTALDH1A1TSHRTDP1CA12 | |
| Ethylenediamine SCHEMBL27892274 | 0.82 | CA12 (0.53) | MAPTALDH1A1TSHRTDP1CA12 | |
| Trimethylammonium SCHEMBL27312264 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117282256-A | Aqueous mixed amine liquid-liquid phase absorbent for capturing carbon dioxide | 四川大学 | 2023-12-26 | — | — | CN | disclosed |