Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propanol SCHEMBL11023591 | 0.85 | MAPT (0.59) | MAPTALDH1A1TSHRTDP1DNM1 | |
| Monoethanolamine SCHEMBL29132870 | 0.85 | MAPT (0.59) | MAPTALDH1A1TSHRTDP1CYP2C9 | |
| Monoethanolamine SCHEMBL6103998 | 0.82 | MAPT (0.56) | MAPTALDH1A1TSHRTDP1CYP2C9 | |
| Dimethylaminoethanol SCHEMBL20677258 | 0.82 | MAPT (0.75) | MAPTALDH1A1TSHRTDP1CYP2C9 | |
| Propylamine SCHEMBL8950354 | 0.82 | CYP2C9 (0.42) | MAPTALDH1A1TSHRTDP1CYP2C9 | |
| Hydroxyamine SCHEMBL29087885 | 0.82 | — | — | |
| Dimethylaminoethanol SCHEMBL11289429 | 0.81 | MAPT (0.63) | MAPTALDH1A1TSHRTDP1CYP2C9 | |
| Monoethanolamine SCHEMBL28485881 | 0.80 | DNM1 (0.68) | ALDH1A1TSHRTDP1DNM1 | |
| Monoethanolamine SCHEMBL7890670 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1TSHRCYP2C9CYP2C19 | |
| Methylamine SCHEMBL16910160 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996771-A | Polyisocyanate composition, coating composition and coated substrate | 旭化成株式会社 | 2021-06-18 | — | — | CN | disclosed |
| EP-1381656-B1 | AQUEOUS CLEANING COMPOSITION CONTAINING COPPER-SPECIFIC CORROSION INHIBITOR FOR CLEANING INORGANIC RESIDUES ON SEMICONDUCTOR SUBSTRATE | ADVANCED TECH MATERIALS (US) | 2010-11-10 | — | — | EP | disclosed |
| EP-1381656-A4 | AQUEOUS CLEANING COMPOSITION CONTAINING COPPER-SPECIFIC CORROSION INHIBITOR FOR CLEANING INORGANIC RESIDUES ON SEMICONDUCTOR SUBSTRATE | ADVANCED TECH MATERIALS (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1381656-A1 | AQUEOUS CLEANING COMPOSITION CONTAINING COPPER-SPECIFIC CORROSION INHIBITOR FOR CLEANING INORGANIC RESIDUES ON SEMICONDUCTOR SUBSTRATE | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002077120-A1 | AQUEOUS CLEANING COMPOSITION CONTAINING COPPER-SPECIFIC CORROSION INHIBITOR FOR CLEANING INORGANIC RESIDUES ON SEMICONDUCTOR SUBSTRATE | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| WO-1998030667-A1 | SEMICONDUCTOR WAFER CLEANING COMPOSITION AND METHOD WITH AQUEOUS AMMONIUM FLUORIDE AND AMINE | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 1998-07-16 | — | — | WO | disclosed |