Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133064 | 0.84 | NOTUM (0.43) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL30622155 | 0.80 | KDM4E (0.52) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL15272014 | 0.80 | KDM4E (0.52) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL5115763 | 0.79 | MAPT (0.58) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL2088807 | 0.76 | MAPT (0.69) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL29133115 | 0.75 | HDAC6 (0.48) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL2090020 | 0.74 | NPC1 (0.57) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL29133063 | 0.74 | ALDH1A1 (0.52) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL30622193 | 0.74 | TLR8 (0.43) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL2096968 | 0.73 | ALDH1A1 (0.60) | KDM4EHPGDALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |