Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325385 | 0.78 | HPGD (0.57) | ALDH1A1HPGDMAPK1NOTUMTSHR | |
| SCHEMBL31488513 | 0.78 | HPGD (0.57) | ALDH1A1HPGDMAPK1NOTUMTSHR | |
| SCHEMBL29133064 | 0.77 | NOTUM (0.43) | ALDH1A1HPGDMAPK1NOTUMTSHR | |
| SCHEMBL29133160 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1HPGDMAPK1NOTUMRAB9A | |
| SCHEMBL29133017 | 0.76 | DGAT1 (0.50) | ALDH1A1HPGDMAPK1NOTUMRAB9A | |
| SCHEMBL1459174 | 0.75 | TSHR (0.62) | ALDH1A1HPGDMAPK1NOTUMTSHR | |
| SCHEMBL30221689 | 0.75 | TSHR (0.62) | ALDH1A1HPGDMAPK1NOTUMTSHR | |
| SCHEMBL30622248 | 0.75 | KDM4E (0.49) | ALDH1A1HPGDMAPK1NOTUMRAB9A | |
| SCHEMBL792274 | 0.73 | PTPN1 (0.36) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL29133117 | 0.73 | HDAC6 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |