SCHEMBL29133335

SCHEMBL29133335

O=Cc1cccc(C2CNCCO2)n1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.47
DRD3 P35462 1/20 0.47
HTR1A P08908 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29133332 0.82 DRD2 (0.47) DRD2DRD3HTR1A
SCHEMBL9770851 0.78 DRD2 (0.50) DRD2DRD3HTR1A
SCHEMBL31116757 0.78 DRD2 (0.50) DRD2DRD3HTR1A
SCHEMBL5347554 0.78 DRD2 (0.54) DRD2DRD3HTR1A
SCHEMBL25182004 0.78 DRD2 (0.54) DRD2DRD3HTR1A
SCHEMBL25181457 0.78 DRD2 (0.54) DRD2DRD3HTR1A
SCHEMBL26154063 0.78 DRD2 (0.50) DRD2DRD3HTR1A
SCHEMBL25171593 0.78 DRD2 (0.54) DRD2DRD3HTR1A
SCHEMBL25177354 0.74 HTR1A (0.53) DRD2DRD3HTR1A
SCHEMBL29226952 0.74 DRD2 (0.50) DRD2DRD3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835865-A CBP/catenin signal transmission path inhibitor and application thereof 3+2 制药有限责任公司 2023-03-21 CN disclosed