Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738053 | 0.91 | HSD11B1 (0.62) | HSD11B1USP30MEN1KMT2AKDM4D | |
| SCHEMBL5242729 | 0.91 | HSD11B1 (0.62) | HSD11B1USP30MEN1KMT2AKDM4D | |
| SCHEMBL26666679 | 0.87 | HSD11B1 (0.54) | HSD11B1USP30HPGDKDM4DSPR | |
| SCHEMBL24684941 | 0.86 | HSD11B1 (0.56) | HSD11B1USP30MEN1KMT2AHPGD | |
| SCHEMBL21997690 | 0.84 | HSD11B1 (0.47) | HSD11B1USP30MEN1KMT2AHPGD | |
| SCHEMBL23795137 | 0.83 | HSD11B1 (0.50) | HSD11B1USP30KDM4DSPRJAK2 | |
| SCHEMBL8912028 | 0.83 | HSD11B1 (0.50) | HSD11B1USP30KMT2AKDM4DSPR | |
| SCHEMBL8716875 | 0.83 | HSD11B1 (0.51) | HSD11B1USP30HPGDKDM4DSPR | |
| SCHEMBL190837 | 0.82 | HSD11B1 (0.47) | HSD11B1USP30KDM4DGPR119JAK2 | |
| SCHEMBL1467761 | 0.82 | HSD11B1 (0.53) | HSD11B1USP30MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820199-A | Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors | 瀚远医药有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117295747-A | Anti-cancer nuclear hormone receptor targeting compounds | 诺维逊生物股份有限公司 | 2023-12-26 | — | — | CN | disclosed |