Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133796 | 0.83 | HSD11B1 (0.54) | HSD11B1GPR119USP30KDM4DSPR | |
| SCHEMBL26666679 | 0.83 | HSD11B1 (0.54) | HSD11B1GPR119USP30KDM4DSPR | |
| SCHEMBL24684941 | 0.82 | HSD11B1 (0.56) | HSD11B1GPR119USP30KDM4DSPR | |
| SCHEMBL5845677 | 0.80 | HSD11B1 (0.58) | HSD11B1GPR119USP30KDM4DSPR | |
| SCHEMBL8912028 | 0.80 | HSD11B1 (0.50) | HSD11B1USP30KDM4DSPR | |
| SCHEMBL2053864 | 0.79 | HSD11B1 (0.47) | HSD11B1GPR119USP30KDM4D | |
| SCHEMBL190837 | 0.79 | HSD11B1 (0.47) | HSD11B1GPR119USP30KDM4D | |
| SCHEMBL27313904 | 0.78 | HSD11B1 (0.50) | HSD11B1GPR119USP30KDM4DSPR | |
| SCHEMBL13738053 | 0.78 | HSD11B1 (0.62) | HSD11B1USP30KDM4DSPR | |
| SCHEMBL21285788 | 0.78 | HSD11B1 (0.69) | HSD11B1GPR119USP30SPRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |